Volume 4, Issue 2 ( Journal of Clinical and Basic Research (JCBR) 2020)                   jcbr 2020, 4(2): 15-19 | Back to browse issues page

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Nasr ali S, Mohammed Omar A M R, Alhama H. Clinical and Histopathological Evaluations of Testicular Regression Syn-drome: A Case Report. jcbr. 2020; 4 (2) :15-19
URL: http://jcbr.goums.ac.ir/article-1-251-en.html
1- Department of Paediatrics, Faculty of Medicine, Minia University, Minia, Egypt؛ Hamad Medical Corporation, Doha, Qatar , sabrynasraly@yahoo.com
2- Department of Pathology, Faculty of Medicine, Minia University, Minia, Egypt;Al Emadi Hospital, Doha, Qatar
3- Department of Paediatric Surgery, Pediatric University Hospital, Damascus, Syria; Al Emadi Hospital, Doha, Qatar
Abstract:   (242 Views)
Background: Testicular regression syndrome (TRS) is defined as the partial or total absence of testicular tissue in 46XY patients with normal external genitalia. The incidence of TRS has been reported to be less than 5% in patients with cryptorchidism. Herein, we report a case of a one-year old boy who underwent surgical exploration with an initial diagnosis of cryptorchidism.
Case description: a one-year old male came to the outpatient clinic at Al Emadi Hospital, Doha, Qatar. Physical examination revealed normal external genitalia with palpable right testis and non-palpable left testis. The initial diagnosis was cryptorchidism. Testicular structure was not identified and a presumed testicular remnant in the left superficial inguinal ring was sent for histological examination. The histological examination revealed a fibrovascular nodule, spermatic cord structures, calcification and hemosiderin deposits supporting the diagnosis of TRS.
Conclusion: When patient fulfills clinical and pathological criteria for TRS, we should consider the possibility of orchiopexy and testicular prosthesis implantation to decrease the risk of testicular torsion and negative psychological effects.
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Article Type: Research | Subject: Basic medical sciences
Received: 2020/07/14 | Accepted: 2020/05/21 | Published: 2020/05/21

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