Volume 5, Issue 4 ( Journal of Clinical and Basic Research (JCBR) 2021)                   jcbr 2021, 5(4): 9-15 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ajagbe͓ A O, Ajenikoko M K, Ajiboye E O. An Overview of the Therapeutic Effects of Environmental Enrichment on Traumatic Brain Injury. jcbr. 2021; 5 (4) :9-15
URL: http://jcbr.goums.ac.ir/article-1-336-en.html
1- Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Nile University of Nigeria, P.M.B. 900001, Abuja, Nigeria , abayomiajagbe4@gmail.com
2- Department of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Western Campus
3- Developmental Neurobiology Unit, Department of Physiology and Anatomy, Ajayi Crowther University, Oyo,Nigeria
Abstract:   (321 Views)
Traumatic brain injury (TBI) occurs due to primary or secondary brain damages that result in temporary or permanent neurological deficits. The sum combined rates for TBI-related emergency department visits, hospitalizations, and deaths have escalated in 2001-2010. Environmental enrichment (EE) is a non-invasive therapy used to enhance learning and memory function. Given its positive effects on neuronal plasticity, EE can be applied as therapy for medical conditions such as neurodegenerative disorders (Parkinson’s, Alzheimer disease) and TBI. This study reviewed the therapeutic effects of EE via music therapy and mastication for treatment of TBI. The introduction of EE in animal studies has been well established compared to human studies. This entails the use of various objects with different shapes, sizes, colors, textures, running wheels, ropes, plastic tunnels, balls, stairs, and shelters as part of this method that enhance physical activity compared with standard housing. Studies have shown that EE boosts cognitive function after TBI. It is also recommended to use wooden dowels as an EE tool in animal brain research.
Full-Text [PDF 536 kb]   (90 Downloads) |   |   Full-Text (HTML)  (78 Views)  
Article Type: Review | Subject: Neuroscience
Received: 2021/10/8 | Accepted: 2021/12/4 | Published: 2021/12/28

References
1. Galaj E, Barrera ED, Ranaldi R. Therapeutic efficacy of environmental enrichment for substance use disorders. Pharmacology Biochemistry and Behavior. 2020; 188:172829. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
2. Herrero MT, Morelli M. Multiple mechanisms of neurodegeneration and progression. Progress in neurobiology. 2017; 155:1. [View at Publisher] [DOI] [PMID] [Google Scholar]
3. Tang BL. Axon regeneration induced by environmental enrichment-epigenetic mechanisms. Neural regeneration research. 2020;15(1):10-15. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
4. Patel TR. Environmental enrichment: aging and memory. The Yale journal of biology and medicine. 2012;85(4):491-500. [Google Scholar]
5. Bayne K. Environmental enrichment and mouse models: current perspectives. Animal models and experimental medicine. 2018;1(2):82-90. [DOI] [PMID] [PMCID] [Google Scholar]
6. Hannan AJ. Environmental enrichment and brain repair: harnessing the therapeutic effects of cognitive stimulation and physical activity to enhance experience‐dependent plasticity. Neuropathology and applied neurobiology. 2014;40(1):13-25. [View at Publisher] [DOI] [PMID] [Google Scholar]
7. Alwis DS, Rajan R. Environmental enrichment and the sensory brain: the role of enrichment in remediating brain injury. Frontiers in systems neuroscience. 2014; 8:156. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
8. Galaj E, Barrera ED, Ranaldi R. Therapeutic efficacy of environmental enrichment for substance use disorders. Pharmacology Biochemistry and Behavior. 2020; 188:172829. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
9. Singhal G, Jaehne EJ, Corrigan F, Baune BT. Cellular and molecular mechanisms of immunomodulation in the brain through environmental enrichment. Frontiers in cellular neuroscience. 2014; 8:97. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
10. Wang KK, Yang Z, Zhu T, Shi Y, Rubenstein R, Tyndall JA et al. An update on diagnostic and prognostic biomarkers for traumatic brain injury. Expert review of molecular diagnostics. 2018;18(2):165-80. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
11. Dang B, Chen W, He W, Chen G. Rehabilitation treatment and progress of traumatic brain injury dysfunction. Neural plasticity. 2017; 2017:1582182. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
12. McKee AC, Daneshvar DH. The neuropathology of traumatic brain injury. Handbook of clinical neurology. 2015; 127:45-66. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
13. Karthivashan G, Park SY, Kweon MH, Kim J, Haque ME, Cho DY et al. Ameliorative potential of desalted Salicornia europaea L. extract in multifaceted Alzheimer's-like scopolamine-induced amnesic mice model. Scientific reports. 2018;8(1):1-6. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
14. Toft M. Advances in genetic diagnosis of neurological disorders. Acta Neurologica Scandinavica. 2014; 129:20-5. doi: 10.1111/ane.12232 [View at Publisher] [DOI] [PMID] [Google Scholar]
15. McMurphy T, Huang W, Queen NJ, Ali S, Widstrom KJ, Liu X et al. Implementation of environmental enrichment after middle age promotes healthy aging. Aging (Albany NY). 2018;10(7):1698-1721. [DOI] [PMID] [PMCID] [Google Scholar]
16. Leon M, Woo C. Environmental enrichment and successful aging. Frontiers in behavioral neuroscience. 2018; 12:155. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
17. Lucke-Wold BP, Logsdon AF, Nguyen L, Eltanahay A, Turner RC, Bonasso P et al. Supplements, nutrition, and alternative therapies for the treatment of traumatic brain injury. Nutritional neuroscience. 2018;21(2):79-91. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
18. Magee WL, Clark I, Tamplin J, Bradt J. Music interventions for acquired brain injury. Cochrane Database of Systematic Reviews. 2017(1). [View at Publisher] [DOI] [Google Scholar]
19. Schlaug G. Musicians and music making as a model for the study of brain plasticity. Progress in brain research.2015;217:37-55. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]
20. Merrett DL, Peretz I, Wilson SJ. Moderating variables of music training-induced neuroplasticity: a review and discussion. Frontiers in psychology. 2013; 4:606. [View at Publisher] [DOI] [PMID] [PMCID] [Google Scholar]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2022 CC BY-NC 4.0 | Journal of Clinical and Basic Research

Designed & Developed by : Yektaweb

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0).