دوره 4، شماره 4 - ( 10-1399 )
جلد 4 شماره 4 صفحات 61-50 |
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Ebrahimi M, Mohebbi A, Mostakhdem Hashemi M, Ashrafi Shahmirzadi M. Prevalence of BK Virus among Iranian Renal Transplant Recipients: A Systematic Review and Meta-Analysis. jcbr 2020; 4 (4) :50-61
URL: http://jcbr.goums.ac.ir/article-1-295-fa.html
URL: http://jcbr.goums.ac.ir/article-1-295-fa.html
Prevalence of BK Virus among Iranian Renal Transplant Recipients: A Systematic Review and Meta-Analysis. Journal of Clinical and Basic Research. 1399; 4 (4) :50-61
چکیده: (3422 مشاهده)
Background and objectives: BK virus (BKV) reactivation is a major challenge for renal transplant recipients. The purpose of this study was to summarize current knowledge on the status of BKV in Iranian renal transplant recipients.
Methods: Specific terms, including “BKV” and “Renal Transplantation” were used to search the online databases. I2 and Cochran’s Q-value were tested for heterogeneity. The incidence rate was determined at 95% confidence interval. Publication bias was also investigated using funnel plot, the Egger’s and Begg’s statics.
Results: Twelve studies were included in the study. The random model's overall evidence rate was 0.347 (CI 95%, 0.225-0.493, p-value=0.04).
Conclusions: In Iran, the estimated prevalence of BKV among renal transplant recipients is 34.7% (~10-60%), which is higher than the rate reported from other parts of the world. Therefore, it is recommended to screen organ donors for BKV in Iran.
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علوم پایه پزشکی
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