1. Infectious Disease Research Center, Golestan University of Medical Sciences, Gorgan, Iran . , dr.tahamtan@goums.ac.ir
Abstract: (3250 Views)
The clinical outcome of coronavirus disease 2019 (COVID-19) varies considerably from one individual to another and severe illness occurs only in a minority of cases. Evidence supports the role of genetic background alongside host, viral and environmental factors for COVID-19 severity. It seems that host genetic background affects the balance of immune responses during SARS-CoV-2 infection, leading to different clinical courses of the disease
References
1. Teymoori-Rad M, Samadizadeh S, Tabarraei A, Moradi A, Shahbaz MB, Tahamtan A. Ten challenging questions about SARS-CoV-2 and COVID-19. Expert review of respiratory medicine. 2020. [
View at Publisher] [
DOI] [
PubMed] [
Google Scholar]
2. Zhou C, Huang Z, Tan W, Li X, Yin W, Xiao Y, et al. Predictive factors of severe coronavirus disease 2019 in previously healthy young adults: a single-center, retrospective study. Respiratory Research. 2020;21(1):157. [
View at Publisher] [
DOI] [
PubMed] [
Google Scholar]
3. Tahamtan A, Samadizadeh S, Rastegar M, Nakstad B, Salimi V. Respiratory syncytial virus infection: why does disease severity vary among individuals? Expert review of respiratory medicine.2020;14(4):415-23.
https://doi.org/10.1080/17476348.2020.1724095 [
View at Publisher] [
DOI] [
PubMed] [
Google Scholar]
4. Williams FM, Freydin M, Mangino M, Couvreur S, Visconti A, Bowyer RC, et al. Self-reported symptoms of covid-19 including symptoms most predictive of SARS-CoV-2 infection, are heritable. medRxiv. 2020.
https://doi.org/10.1101/2020.04.22.20072124 [
View at Publisher] [
DOI] [
PubMed] [
Google Scholar]