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:: Volume 2, Issue 2 (Journal of Clinical and Basic Research(JCBR) 2018) ::
jcbr 2018, 2(2): 1-4 Back to browse issues page
A Case of Idiopathic Thrombocytopenic Purpura during Pregnancy
Maryam Moradi , Fatemeh Chorli , Leila Asadi
Abstract:   (35 Views)
Background: Idiopathic thrombocytopenic purpura (ITP) is one of the common causes of thrombocytopenia in the first and second trimesters of pregnancy. Herein, we report a pregnant woman with ITP with the aim to review the latest evaluation and treatment methods for ITP in the third trimester of pregnancy. Case description: The patient was a 23-year-old G2 P1 woman with gestational age of 33 weeks and 4 days, who was referred to hospital due to reduced platelet count (21,000) in the pregnancy screening tests. The patient was subjected to splenectomy after 3 weeks at gestational age of 36 weeks and 4 days, and cesarean section was performed concurrently to terminate the pregnancy. The patient was transferred to the ICU after surgery and was stable. The wound site was normal. Within a few days after the surgery, platelet levels increased to 80,000. Finally, the patient was discharged in a good general condition two weeks after the cesarean section, and was prescribed to take 5 mg prednisolone daily. Conclusion: ITP should be considered in all patients who are first diagnosed with single thrombocytopenia during pregnancy, especially if the condition is detected before the third trimester and with platelet count of less than 50,000. Depending on the course of the disease, patients should be thoroughly monitored for platelet levels for timely treatment.
Keywords: Pregnancy, Idiopathic thrombocytopenic purpura, Platelet
Full-Text [PDF 376 kb]   (22 Downloads)    
Type of Study: case report |
Received: 2018/08/2 | Accepted: 2018/08/2 | Published: 2018/08/2
References
1. Myers B. Diagnosis and management of maternal thrombocytopenia in pregnancy. Br J Haematol. 2012;158:3–15. [DOI:10.1111/j.1365-2141.2012.09135.x]
2. Abrahamson PE, Hall SA, Feudjo-Tepie M, et al. The incidence of idiopathic thrombocytopenic purpura among adults: a population-based study and literature review. Eur J Haematol. 2009;83:83–89. [DOI:10.1111/j.1600-0609.2009.01247.x]
3. Gernsheimer T, James A H, Stasi R. How I treat thrombocytopenia in pregnancy. Blood. 2013;121:38–47. [DOI:10.1182/blood-2012-08-448944]
4. Thienelt CD, Calverley DC. Thrombocytopenia Caused by Immunologic Platelet Distruction. Wintrobes Clinical Hematology 2009;II(Chapter 51).
5. Delmas Y, Helou S, Chabanier P, Ryman A, Pelluard F, Carles D, et al. Incidence of obstetrical thrombotic thrombocytopenic purpura in a retrospective study within thrombocytopenic pregnant women. A difficult diagnosis and a treatable disease. BMC Pregnancy Childbirth 2015; 15:137. [DOI:10.1186/s12884-015-0557-5]
6. Matthews JH, Benjamin S, Gill DS, Smith NA. Pregnancy-associated thrombocytopenia: definition, incidence and natural history. Acta Haematol 1990; 84(1): 24-29. [DOI:10.1159/000205022]
7. Zhang MM, Jiang B. Clinical analysis of 60 cases of pregnancy with thrombocytopenia. Zhonghua Fu Chan Ke Za Zhi 1992; 27(4): 224-226, 250-251.
8. Modarresnejad V, Motamedi B. Study of the Prevalence of Thrombocytopenia and Factors Affecting it in Kerman. Asrar 2001; 9(2): 4- 10 (Persian).
9. Yazdani Sh, Bouzari Z, Sedaghat S., Abedi Samaquosh, Farajnejad K. Prevalence of thrombocytopenia in pregnancy and its related factors. IJOGI, Vol. 19, No. 32, pp. 20-24, Nov 2016.
10. Stavrou E, McCrae KR. Immune thrombocytopenia in pregnancy. Hematol Oncol Clin North Am 2009;23:1299–316. [DOI:10.1016/j.hoc.2009.08.005]
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Moradi M, Chorli F, Asadi L. A Case of Idiopathic Thrombocytopenic Purpura during Pregnancy. jcbr. 2018; 2 (2) :1-4
URL: http://jcbr.goums.ac.ir/article-1-136-en.html


Volume 2, Issue 2 (Journal of Clinical and Basic Research(JCBR) 2018) Back to browse issues page
Journal of Clinical and Basic Research Journal of Clinical and Basic Research
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