fa Statistics and epidemiology پژوهشي Research <div style="text-align: justify;">Human cytomegalovirus (CMV) isa ubiquitous organism thatcan infect multiple organs butrarely causes gastrointestinal (GI) symptoms. However, it can be reactivated in the GI tractand lead to gastric cancer. Here, we investigatedCMV infection in patients with gastric complaints.<strong>Material and methods:</strong>In this study,99 biopsy samples were collected from patientswith GI symptoms and CMV genome was detected by polymerase chain reaction. Sequencing was performed for computational genotyping.<strong>Results:</strong>We observed that 88.99% of the sampleswere urease positive and 5.99% of<a name="_GoBack"></a> the sampleswere CMV positive. Moreover, genotype of the samples belonged to group 4 (gB4). There was a relatively high incidence of CMV infection in patients with GI problems. <strong>Conclusions:</strong>Although symptomatic CMV-associated diseases of GI tract are rare in immunocompetent individuals, theymight be considered as potential complications of CMV infection.</div> Human cytomegalovirus, Gastrointestinal infection, Gastric biopsy, Urease positive 11 15 http://jcbr.goums.ac.ir/browse.php?a_code=A-10-88-2&slc_lang=fa&sid=1 Mojtaba Pourmomen مجتبی پور مومن 10031947532846001657 10031947532846001657 No Department of Microbiology, Islamic Azad University, Gorgan branch, Gorgan, Iran Alireza Mohebbi علیرضا محبی 10031947532846001658 10031947532846001658 No Student Research Committee, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran Hanieh Bagheri هانیه باقری 10031947532846001659 10031947532846001659 No Infectious Diseases Research Centre, Golestan University of Medical Science, Gorgan, Iran Alireza Nourozi علیرضا نوروزی 10031947532846001660 10031947532846001660 No Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran Alireza Tahamtan علیرضا تهمتن 10031947532846001661 10031947532846001661 No Golestan University of Medical Sciences, Gorgan, Iran Mohammad Yasaghi محمد یساقی 10031947532846001662 10031947532846001662 No Student Research Committee, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran Hamidreza Pordeli حمیدرضا پردل 10031947532846001663 10031947532846001663 No Department of Microbiology, Islamic Azad University, Gorgan branch, Gorgan, Iran Alijan Tabarraei علیجان تبرائی 10031947532846001664 10031947532846001664 Yes Infectious Diseases Research Centre, Golestan University of Medical Science, Gorgan, Iran