Volume 5, Issue 3 ( Journal of Clinical and Basic Research (JCBR) 2021)
jcbr 2021, 5(3): 21-24 |
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alimadadi M, Mohajernoei S, Raghimi H. Chronic Diarrhea as the Sole Symptom of HIV Infection: A Case Report. jcbr 2021; 5 (3) :21-24
URL: http://jcbr.goums.ac.ir/article-1-320-en.html
URL: http://jcbr.goums.ac.ir/article-1-320-en.html
1- 1. Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran , alimadadi1360@yahoo.com
2- Department of Medical Sciences, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
2- Department of Medical Sciences, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
Abstract: (1547 Views)
Background: Acquired immunodeficiency syndrome (AIDS) is a disease caused by the human immunodeficiency virus (HIV) that can affect all systems of the human body. Considering that there is no definitive treatment for AIDS, timely and accurate diagnosis is important. Symptoms of HIV infection may sometimes be nonspecific and should always be considered in high-risk individuals. We herein report a patient with HIV who was presented with chronic diarrhea as the sole symptom of HIV Infection.
Case description: A 40 years old man was admitted to hospital with complain of diarrhea that had started seven months ago. He also experienced extensive weight loss and complained of vomiting and abdominal pain in the past month without any fever. Abdominal computed tomography scan and colonoscopy and stool examination were normal. However, biopsy indicated active colitis. Laboratory tests for HIV, functional expression of the lymphoid chemokines, and anti-tissue transglutaminase antibody were negative, but hepatitis C viral load was positive. Because the patient had many tattoos on his body that were done in unsanitary places, AIDS was suspected. The related test was requested, and the result was positive. Finally the patient was prescribed with co-trimoxazole and referred to an AIDS consultation center.
Conclusion: We presented a case of HIV infection with chronic diarrhea as the only symptom without any others clinical findings. Our observations suggest that for better diagnosis and management of HIV infection, it is important to consider chronic diarrhea as one of the important complications of HIV even when not accompanied with any other symptom.
Case description: A 40 years old man was admitted to hospital with complain of diarrhea that had started seven months ago. He also experienced extensive weight loss and complained of vomiting and abdominal pain in the past month without any fever. Abdominal computed tomography scan and colonoscopy and stool examination were normal. However, biopsy indicated active colitis. Laboratory tests for HIV, functional expression of the lymphoid chemokines, and anti-tissue transglutaminase antibody were negative, but hepatitis C viral load was positive. Because the patient had many tattoos on his body that were done in unsanitary places, AIDS was suspected. The related test was requested, and the result was positive. Finally the patient was prescribed with co-trimoxazole and referred to an AIDS consultation center.
Conclusion: We presented a case of HIV infection with chronic diarrhea as the only symptom without any others clinical findings. Our observations suggest that for better diagnosis and management of HIV infection, it is important to consider chronic diarrhea as one of the important complications of HIV even when not accompanied with any other symptom.
Article Type: Case report |
Subject:
Medicine
References
1. Price WA, Forejt J. Neuropsychiatric aspects of AIDS: a case report. General hospital psychiatry. 1986 Jan 1;8(1):7-10. [View at Publisher] [DOI] [PubMed] [Google Scholar]
2. Gottlieb MS, Schroff R, Schanker HM, Weisman JD, Fan PT, Wolf RA, Saxon A. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. New England Journal of Medicine. 1981 Dec 10;305(24):1425-31. [View at Publisher] [DOI] [PubMed] [Google Scholar]
3. HIV.gov. What are HIV and AIDS?. June 05, 2020 .https://www.hiv.gov/hiv-basics/overview/about-hiv-and-aids/what-are-hiv-and-aids.
4. Scutchfield FD, Benenson AS. AIDS update. Postgrad Med. 1989 Mar;85(4):289-94. [View at Publisher] [DOI] [PubMed] [Google Scholar]
5. Patel TS, Crutchley RD, Tucker AM, Cottreau J, Garey KW. Crofelemer for the treatment of chronic diarrhea in patients living with HIV/AIDS. HIV/AIDS (Auckland, NZ). 2013;5:153. [View at Publisher] [DOI] [PubMed] [Google Scholar]
6. sTwisha S Patel, Rustin D Crutchley, Anne M Tucker, Jessica Cottreau, Kevin W Garey. Crofelemer for the treatment of chronic diarrhea in patients living with HIV/AIDS. HIV AIDS (Auckl). 2013; 5: 153-162. [View at Publisher] [DOI] [PubMed] [Google Scholar]
7. Barrett KE, Keely SJ. Chloride secretion by the intestinal epithelium: molecular basis and regulatory aspects. Annual review of physiology. 2000 Mar;62(1):535-72. [View at Publisher] [DOI] [PubMed] [Google Scholar]
8. Hardy WD. Fundamentals of HIV Medicine 2019. Oxford University Press, USA; 2019 Jun 10. [View at Publisher] [Google Scholar]
9. Noor A, Bedi D, Yassin MH. Multiorganism HIV-associated diarrhea and telescoping bowel. InBaylor University Medical Center Proceedings 2020 Jul 2 (Vol. 33, No. 3, pp. 386-388). Taylor & Francis. [View at Publisher] [DOI] [PubMed] [Google Scholar]
10. Pollack TM, et al. Primary care of the HIV-infected adult. https://www.uptodate.com/contents/search. Accessed Dec. 6, 2019
11. Sánchez-Mejorada G, Ponce-de-Leon S. Clinical patterns of diarrhea in AIDS: etiology and prognosis. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 1994 May 1;46(3):187-96. [View at Publisher] [PubMed] [Google Scholar]
12. Hall VP. Common Gastrointestinal Complications Associated with Human Immunodeficiency Virus/AIDS: An Overview. Critical care nursing clinics of North America. 2017 Dec 6;30(1):101-7. [View at Publisher] [DOI] [PubMed] [Google Scholar]
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