[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 3, Issue 3 ( Journal of Clinical and Basic Research (JCBR) 2019) ::
jcbr 2019, 3(3): 12-17 Back to browse issues page
A Case Report of a Patient with Postpartum HELLP Syndrome
Maryam Moradi1 , Behjat Khorsandi2 , Mohadese Motaharinejad 2
1- Counseling Center for Midwifery and Reproductive Health, Golestan University of Medical Sciences, Gorgan, Iran
2- School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
Abstract:   (433 Views)
Background: HELLP syndrome is a multisystemic disorder characterized by elevated liver enzymes, hemolysis and low platelet count. If left untreated, it is associated with high risk of maternal and fetal mortality. It usually occurs in the third trimester of pregnancy but may sometimes occur after pregnancy. Herein, we report a patient with postpartum HELLP syndrome.
Case description: A 32-year-old woman (G2Ab1) with gestational age of 36 weeks and a history of hypothyroidism, multiple sclerosis, favism, gestational diabetes and pregnancy-induced hypertension was admitted to hospital due to labor pain. The patient underwent cesarean section and showed triad of postpartum HELLP syndrome. Fortunately, with timely diagnosis and appropriate intervention, the patient was discharged with good general condition after four days of hospitalization in intensive care unit.
Conclusion: Pregnancy-induced hypertension is a life-threatening condition for mothers. HELLP syndrome is often related to preeclampsia but can also occur as a stand-alone disorder. Absence of symptoms should not rule out this syndrome, and it is recommended to consider risk of postpartum HELLP syndrome during follow ups.
Keywords: HELLP syndrome, Preeclampsia
Full-Text [PDF 182 kb]   (115 Downloads)    
Article Type: Case report | Subject: Medicine
Received: 2019/10/3 | Accepted: 2019/10/3 | Published: 2019/10/3
1. Rath W, Faridi A, Dudenhausen JW. HELLP syndrome. Journal of perinatal medicine. 2000 ;28(4):249-60. [DOI:10.1515/JPM.2000.033]
2. Shirazi M, Help Syndrome. Iranian Journal of Obstetrics and Gynecology. 2011; 6(2):18-25. [In Persian]
3. Sibai BM, Taslimi MM, El-Nazer A, Amon E, Mabie BC, Ryan GM. Maternal-perinatal outcome associated with the syndrome of hemolysis, elevated liver enzymes, and low platelets in severe preeclampsia-eclampsia. American journal of obstetrics and gynecology. 1986;155(3):501-7. [DOI:10.1016/0002-9378(86)90266-8]
4. Hund M, Allegranza D, Schoedl M, Dilba P, Verhagen-Kamerbeek W, Stepan H. Multicenter prospective clinical study to evaluate the prediction of short-term outcome in pregnant women with suspected preeclampsia (PROGNOSIS): study protocol. BMC pregnancy and childbirth. 2014 Dec;14(1):324. [DOI:10.1186/1471-2393-14-324]
5. Rao D, Chaudhari NK, Moore RM, Jim B. HELLP syndrome: a diagnostic conundrum with severe complications. BMJ case reports. 2016;2016:bcr2016216802. [DOI:10.1136/bcr-2016-216802]
6. Rimaitis K, Grauslyte L, Zavackiene A, Baliuliene V, Nadisauskiene R, Macas A. Diagnosis of HELLP Syndrome: A 10-Year Survey in a Perinatology Centre. International journal of environmental research and public health. 2019;16(1):109. [DOI:10.3390/ijerph16010109]
7. Haram K, Svendsen E, Abildgaard U. The HELLP syndrome: clinical issues and management. A Review. BMC pregnancy and childbirth. 2009;9(1):8. [DOI:10.1186/1471-2393-9-8]
8. Malvino E, Munoz M, Ceccotti C, Janello G, Mc DL, Pawlak A, Desmery P, Lopez OG. Maternal morbidity and perinatal mortality in HELLP syndrome. Multicentric studies in intensive care units in Buenos Aires area. Medicina. 2005;65(1):17-23.
9. Mao M, Chen C. Corticosteroid therapy for management of hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome: a meta-analysis. Medical science monitor: international medical journal of experimental and clinical research. 2015;21:3777. [DOI:10.12659/MSM.895220]
10. Levin G, Kalish Y, Attari R, Khatab AA, Gil M, Rottenstreich A. Plasmapheresis-A lifesaving treatment for life threatening HELLP syndrome. European Journal of Obstetrics and Gynecology and Reproductive Biology. 2019 Apr 1;235:125-6. [DOI:10.1016/j.ejogrb.2018.08.583]
11. Habli M, Eftekhari N, Wiebracht E, Bombrys A, Khabbaz M, How H, Sibai B. Long-term maternal and subsequent pregnancy outcomes 5 years after hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. American journal of obstetrics and gynecology. 2009;201(4):385-e1. [DOI:10.1016/j.ajog.2009.06.033]
12. Chames MC, Haddad B, Barton JR, Livingston JC, Sibai BM. Subsequent pregnancy outcome in women with a history of HELLP syndrome at≤ 28 weeks of gestation. American journal of obstetrics and gynecology. 2003 ;188(6):1504-8. [DOI:10.1067/mob.2003.383]
13. Sibai BM, Ramadan MK, Chri RS, Friedman SA. Pregnancies complicated by HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): subsequent pregnancy outcome and long-term prognosis. American journal of obstetrics and gynecology. 1995;172(1):125-9. [DOI:10.1016/0002-9378(95)90099-3]
Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Moradi M, Khorsandi B, Motaharinejad M. A Case Report of a Patient with Postpartum HELLP Syndrome. jcbr. 2019; 3 (3) :12-17
URL: http://jcbr.goums.ac.ir/article-1-223-en.html

Volume 3, Issue 3 ( Journal of Clinical and Basic Research (JCBR) 2019) Back to browse issues page
Journal of Clinical and Basic Research Journal of Clinical and Basic Research
Persian site map - English site map - Created in 0.06 seconds with 31 queries by YEKTAWEB 4075