Journal of Clinical and Basic Research (JCBR)

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Hosseininejad S, Gharanjik A, Taziki S, Kalantari S, Hosseininejad F, Salimi Kordasiabi A. Frequency of Psychiatric Disorders in Drug Addicts and Non-addicts: A Case-Control Study. jcbr 2017; 1 (4) :31-35
URL: http://jcbr.goums.ac.ir/article-1-116-en.html

Background: Addiction (drug dependence) is a health problem in many countries. In Iran, drug abuse is one of the most important preventable health problems. Comorbidity of drug abuse with other disorders is also a barrier to treatment of addicts, in a way that more than 70% of addicts suffer from mental and physical disorders. Therefore, we performed this comparative study to investigate the comorbidity of mental disorders in drug-dependent and non-dependent individuals referred to the addiction rehab center of 5^th Azar Hospital in Gorgan, in 2016. Materials and Methods: The study was performed on 130 male drug addicts and 130 male healthy controls through available sampling. Structured interviews for drug dependence testing (based on the DSM-V-TR criteria) and the symptom checklist-90-Revised (SCL-90-R) were used to assess the mental status of the subjects. Data were analyzed using SPSS (version 16) via t-test, man-witny, chi-square and Shapiro-Wilk. The significance level (P) was set at 0.05 and validity and reliability of the material were evaluated in a pilot investigating. Results: The subjects with drug-dependence scored higher in all scales related to mental disorders compared with the control group. The frequency of symptoms including somatization (56.9%), obsessive-compulsive disorder (61.5%), interpersonal sensitivity (62.3%), depression (66.2%), anxiety (59.2%), hostility (42.3%), phobia (34.5%), paranoid ideation (62.6%), and psychoticism (56.9%) was higher in subjects with drug addiction. Conclusion: The results of this study indicate that the frequency of psychopathological symptoms and mental disorders is significantly higher in drug-dependent individuals compared with the normal population.