en Nursing پژوهشي Research <div style="text-align: justify;"><strong>Background and objectives:</strong> Patient safety culture is one of the basic principles of health care. Nurses are the first to be involved in the implementation of this culture in clinical settings. The aim of this study was to determine effect of in-person and E-training on patient safety culture of nurse managers working in hospitals affiliated to the Golestan University of Medical Sciences, Golestan Province, Iran.<br> <strong>Methods:</strong> This semi-experimental study was conducted on 60 nurse managers working in hospitals affiliated to the Golestan University of Medical Sciences in 2012. The subjects were randomly divided into an in-person training group and an E-training group. Data were collected using the patient safety culture questionnaire (originally designed by Liane Ginsburg). SPSS (version 16) was used for analysis of data using descriptive and inferential statistics.<br> <strong>Results:</strong> After the training intervention, the patient safety culture improved significantly in both groups (P<0.001). However, the mean score of patient safety culture in the in-person training group was significantly higher than that in the E-training group (P<0.03).<br> <strong>Conclusion:</strong>&nbsp; The results of this study showed that both training programs are beneficial for promoting the patient safety culture in nurse managers. Since the support, commitment and understanding of hospital managers are crucial for creating a positive safety culture, managers can provide planned strategies for improving patient safety.</div> Patient safety, safety culture, nurse managers, hospitals 34 39 http://jcbr.goums.ac.ir/browse.php?a_code=A-10-87-2&slc_lang=en&sid=1 Gholamreza Mahmodi Shan غلامرضا محمودی شن 10031947532846002068 10031947532846002068 No School of Nursing and Midwifery, Golestan University of Medical Sciences, Gorgan, Iran Zahra Royani زهرا رویانی 10031947532846002069 10031947532846002069 No Department of Surgical Technology, Faculty of Paramedical Sciences, Golestan University of Medical Sciences, Gorgan, Iran Farhad Kord فرهاد کرد 10031947532846002070 10031947532846002070 No Department of Treatment, Golestan University of Medical Sciences, Gorgan, Iran Sakine Beygom Kazemi سکینه بیگم کاظمی 10031947532846002071 10031947532846002071 No Department of Treatment, Golestan University of Medical Sciences, Gorgan, Iran Samieh Ghana سامیه غنا 10031947532846002072 10031947532846002072 No School of Nursing and Midwifery, Golestan University of Medical Sciences, Gorgan, Iran Shima Rahimian شیما رحیمیان 10031947532846002073 10031947532846002073 No School of Nursing and Midwifery, Golestan University of Medical Sciences, Gorgan, Iran Soheyla Kalantary سهیلا کلانتری 10031947532846002074 10031947532846002074 Yes Department of Surgical Technology, Faculty of Paramedical Sciences, Golestan University of Medical Sciences, Gorgan, Iran Navisa Seyed Ghasemi نویسا سیدقاسمی 10031947532846002075 10031947532846002075 No Department of Biostatistics, Golestan University of Medical Sciences, Gorgan, Iran